Founded in 2015 by Stefania Sabella, the mission of the group is highly cross-disciplinary requiring a strong integration of scientific knowledge of the emerging contaminants such as nanomaterials in the food, nanoplastics and drugs (physicochemical properties, exposure, fate and hazard) to regulatory understanding. Each research activity focuses on risk assessment linking the physicochemical properties (and related functionalities) to potential induced hazard on humans.
Current research interests include:
- Analytical tools for identification and quantification of biotransformation of emerging contaminants in artificial human milieu e.g., the internal body fluids (saliva, stomach, intestine, lung fluids, lysosome and sweat).
- In vitro assays predictive of in vivo toxicity as for example dissolution in relevant human simulant body fluids and their relationship to biopersistence and potential relevant health impact of novel materials.
- 2D and 3D cellular models for toxicity studies of bionanomaterials and drugs (gut, lung, liver).
- Integrated Approaches to Testing and Assessment (IATA) as supportive analytical tools for risk classification.